Erweiterte Suche. Springer Medizin. Zurück zum Suchergebnis. Wichtige Hinweise. Abstract Background In recent years, tuberculosis outbreaks in schools have occurred more frequently in China than in other parts of the world, and have posed a public health threat to students and their families.
This systematic review aimed to understand the epidemiological characteristics of tuberculosis TB outbreaks and analyze the factors associated with TB outbreaks in schools in China. Methods We conducted this systematic review following the standard procedures of the Cochrane Collaboration and the Preferred Reporting Items for Systematic Review and Meta-Analysis statement. Results We included studies involving student patients with TB in mainland China.
The results of the systematic analysis indicated that TB outbreaks were more frequently reported in senior middle schools and in Eastern China. The meta-analysis showed that the total attack rate and the class attack rate of tuberculosis outbreaks among students were 4. Subgroup analysis showed that outbreaks that occurred at universities or colleges had a relatively higher attack rate than those occurred in senior middle schools.
The prevalence of latent tuberculosis infection LTBI among close contacts was Conclusion The results of our review indicated that school TB outbreaks were reported most frequently in senior middle schools in China.
The attack rates of outbreaks at universities or colleges were higher than those in senior middle schools. The TB outbreaks in schools usually occurred over prolonged periods. The case-finding delay in the index cases must be reduced to prevent transmission in classes and schools. Effective surveillance and screening of presumptive TB cases in schools should be strengthened to reduce outbreaks in schools.
